• Users Online: 260
  • Print this page
  • Email this page
ORIGINAL ARTICLES
Year : 2021  |  Volume : 9  |  Issue : 3  |  Page : 103-106

Relationship of biofilm formation and antibiotic susceptibility profile of uropathogenic Escherichia coli


Department of Microbiology, Dr. Harvansh Singh Judge Institute of Dental Sciences & Hospital, Panjab University, Chandigarh, India

Correspondence Address:
Jyoti Sharma
Department of Microbiology, Dr. Harvansh Singh Judge Institute of Dental Sciences & Hospital, Panjab University, Panjab University South Campus, Vidya Path, Near UIET, Sector 25, Chandigarh 160014
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/dypj.dypj_54_21

Rights and Permissions

Introduction: Escherichia coli is the most frequent etiological agent isolated from urinary tract infections. Ability of these bacteria to form biofilm is one of its important virulence factors. Moreover in the past decades, there has been a growing increase in the prevalence of antibiotic resistance against commonly prescribed antibiotics. Bacteria in biofilm are considered to be highly resistant to antimicrobial agents. Materials and Methods: All the urine isolates were cultured to isolate the etiological agent of the infection and were tested for their susceptibility against various antibiotics recommended for their treatment. Of these isolates, only E. coli were subjected for biofilm formation detection. The resistance pattern obtained after antibiotic susceptibility testing was correlated with the results obtained from biofilm detection. All the results were statistically analyzed. Results: Of all the isolated obtained after culturing urine samples, 90% of them turned out to be E. coli only. When these isolates were subjected to biofilm detection, 35% of them showed positive results. Further, their resistance pattern revealed that bacteria-forming biofilms were more resistant toward penicillins, cephalosporins, and fluoroquinolones where very little resistance was reported for aminoglycosides, carbapenems, and nitrofurantoins. Conclusion: As this study concludes a positive association between biofilm formation and antibiotic resistance, it is strongly suggested that detection of biofilm and awareness about the susceptibility pattern of the bacteria toward locally prescribed antibiotics can be helpful in improving the efficacy of the empirical treatment of types of infections.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed206    
    Printed2    
    Emailed0    
    PDF Downloaded24    
    Comments [Add]    

Recommend this journal